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CNGA2 Rabbit pAb (bs-1785R)  
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產(chǎn)品編號 bs-1785R
英文名稱 CNGA2 Rabbit pAb
中文名稱 環(huán)核苷酸陽離子通道蛋白α2抗體
別    名 CNCA; CNCA1; CNG2; FLJ46312; OCNC1; OCNCa; OCNCALPHA; olfactory cyclic nucleotide-gated ion channel alpha subunit; olfactory ion channel protein; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; CNG channel alpha-2; CNG-2; Cyclic nucleotide-gated olfactory channel subunit OCNC1; CNGA2_HUMAN.  
研究領(lǐng)域 心血管  神經(jīng)生物學(xué)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 73 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CNGA2 : 193-270/664 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 dorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. CNGA2 belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family and contains one cyclic nucleotide-binding domain. It may be involved in odorant signal transduction. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.

Function:
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily.
Contains 1 cyclic nucleotide-binding domain.

SWISS:
Q16280

Gene ID:
1260

Database links:

Entrez Gene: 1260 Human

Entrez Gene: 12789 Mouse

Entrez Gene: 25411 Rat

Omim: 300338 Human

SwissProt: Q16280 Human

SwissProt: Q62398 Mouse

SwissProt: Q00195 Rat

Unigene: 447360 Human

Unigene: 5097 Mouse

Unigene: 10384 Rat



環(huán)核苷酸陽離子通道蛋白α2為陽離子通道結(jié)構(gòu)蛋白。
產(chǎn)品圖片
Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti- CNGA2 (bs-1785R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 73 kD Observed band size: 73 kD
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