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FVT1 Rabbit pAb (bs-13233R)  
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50ul/1180.00元
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200ul/2800.00元
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產(chǎn)品編號 bs-13233R
英文名稱 FVT1 Rabbit pAb
中文名稱 濾泡型轉運蛋白1/II型慢性淋巴性白血病抗體
別    名 3 dehydrosphinganine reductase; 3 ketodihydrosphingosine reductase; 3-dehydrosphinganine reductase; 3-ketodihydrosphingosine reductase; DHSR; FLJ36555; FLJ92680; Follicular lymphoma variant translocation 1; Follicular variant translocation protein 1; FVT 1; FVT-1; FVT1; KDS reductase; KDSR; KDSR_HUMAN; SDR35C1; Short chain dehydrogenase/reductase family 35C member 1.  
研究領域 腫瘤  細胞生物  轉運蛋白  細胞類型標志物  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog)
產(chǎn)品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FVT1: 41-140/332 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).

Function:
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.

DISEASE:
Note=A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

SWISS:
Q06136

Gene ID:
2531

Database links:

Entrez Gene: 505558 Cow

Entrez Gene: 2531 Human

Entrez Gene: 70750 Mouse

Entrez Gene: 360833 Rat

Omim: 136440 Human

SwissProt: Q2KIJ5 Cow

SwissProt: Q06136 Human

SwissProt: Q6GV12 Mouse



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